Quantitative Imaging Biomarkers for 90Y Distribution on Bremsstrahlung SPECT After Resin-Based Radioembolization
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چکیده
منابع مشابه
Quantitative Comparison of PET and Bremsstrahlung SPECT for Imaging the In Vivo Yttrium-90 Microsphere Distribution after Liver Radioembolization
BACKGROUND After yttrium-90 ((90)Y) microsphere radioembolization (RE), evaluation of extrahepatic activity and liver dosimetry is typically performed on (90)Y Bremsstrahlung SPECT images. Since these images demonstrate a low quantitative accuracy, (90)Y PET has been suggested as an alternative. The aim of this study is to quantitatively compare SPECT and state-of-the-art PET on the ability to ...
متن کاملQuantitative SPECT and planar 32P bremsstrahlung imaging for dosimetry purpose –An experimental phantom study
Background: In this study, Quantitative 32P bremsstrahlung planar and SPECT imaging and consequent dose assessment were carried out as a comprehensive phantom study to define an appropriate method for accurate Dosimetry in clinical practice. Materials and Methods: CT, planar and SPECT bremsstrahlung images of Jaszczak phantom containing a known activity of 32P were acquired. In addition, Phanto...
متن کاملSPECT/CT 90Y-Bremsstrahlung images for dosimetry during therapy
BACKGROUND the characteristics of (90)Y, suitable for therapy, are denoted by the lack of γ-emission. Alternative methods, using analogues labelled with (111)In or (86)Y, are generally applied to image (90)Y-conjugates, with some inevitable drawbacks. New generation SPECT/CT image systems offer improved Bremsstrahlung images. The intent of this brief communication is to show that high quality (...
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UNLABELLED Planning hepatic (90)Y radioembolization activity requires balancing toxicity with efficacy. We developed a dual-tracer SPECT fusion imaging protocol that merges data on radioactivity distribution with physiologic liver mapping. METHODS Twenty-five patients with colorectal carcinoma and bilobar liver metastases received whole-liver radioembolization with resin microspheres prescrib...
متن کاملA Comparison of Techniques for 90Y PET/CT Image-Based Dosimetry Following Radioembolization with Resin Microspheres
(90)Y PET/CT following radioembolization has recently been established as a viable diagnostic tool, capable of producing images that are both quantitative and have superior image quality than alternative (90)Y imaging modalities. Because radioembolization is assumed to be a permanent implant, it is possible to convert quantitative (90)Y PET image sets into data representative of spatial committ...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2019
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.118.219691